Teduglutide

[HIGHLIGHT=#f4f4f4] [/HIGHLIGHT] Teduglutide is a 33-membered polypeptide and glucagon-like peptide-2 (GLP-2) analog that is used for the treatment of short bowel syndrome. It works by promoting mucosal growth and possibly restoring gastric emptying and secretion.




Teduglutide differs from natural GLP-2 by a single amino acid: an alanine is replaced with a glycine. This blocks breaking down of the molecule by dipeptidyl peptidase and increases its half-life from seven minutes (GLP-2) to about two hours, while retaining its biological actions. These include maintenance of the intestinal mucosa, increasing intestinal blood flow, reducing gastrointestinal motility and secretion of gastric acid.

[HIGHLIGHT=#f4f4f4] [/HIGHLIGHT] [HIGHLIGHT=#f4f4f4]Creative peptides is specialized in the process development and the manufacturing of bioactive peptides. We offer custom peptide synthesis, process development, GMP manufacturing as well as catalog products. We provide Teduglutide. More information please visit the website:http://www.creative-peptides.com/product/teduglutide-item-m3412132-21367.html[/HIGHLIGHT]